Peoplesoft Windows Application Server Setup

Just curious how other companies setup their Windows Application server for Peoplesoft ?   Did you load all of your directories on your C: drive ?   Was a D: drive used?

How big is your C: drive ?   I know Oracle recommends loading your directory structure on the C: drive, but the operating system also exists there. Has anyone experienced any issues with that setup ?   We hate to continue using this structure (everything on C: drive) if there are potential issues we overlooked.  Thanks SO much, in advance, for sharing your setup.

On Windows based installations I/we alway use the D-drive (or any other drive not running Windows). Also for PUM installations. Never had issues with such setup.

Note: supporting 'general' software like Office/Excel we generally do install on C (but we also use sometimes diffrent drives).